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Home > Products >  17 β-Estradiol;Estradiol

17 β-Estradiol;Estradiol CAS NO.50-28-2

  • Min.Order: 1 Kilogram
  • Payment Terms: T/T,MoneyGram
  • Product Details

Keywords

  • 17 β-Estradiol
  • Estradiol
  • estradiol

Quick Details

  • ProName: 17 β-Estradiol;Estradiol
  • CasNo: 50-28-2
  • Molecular Formula: C18H24O2
  • Appearance: white powder
  • Application: intermediate
  • DeliveryTime: 3-10 workdays
  • PackAge: Aluminum foil bag packaging
  • Port: ShangHai Shenzhen
  • ProductionCapacity: 600 Kilogram/Week
  • Purity: 99.9
  • Storage: keep in cool and dry
  • Transportation: by sea by air
  • LimitNum: 1 Kilogram

Superiority

1,Best Quality:
Our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other countries, and we have got very good feedback from our customers.so you can trust us.
2, Payment method: for example MoneyGram, Westerm Union,other
3, Excellent Service: Best service and after-sales service to all clients.
   1)We will ship the goods within 5days after get your payments.If you want to cancel or change order, please tell me within 24hours after you finish the payment..
   2)We will ship the goods that you order from us by DHL, UPS, TNT and EUB.We will decided to choose which courier depend on different countries.To find the best way to delivery the goods for you.
   3)As usual you can get the goods with in 4-7days.If the goods were lost or not received for other reasons, please contact us immediately.
4,Fast and safe delivery:
Sample Order : As usual you can get the goods within 4-7days. We can send it via HKems, HK Air Post, DHL or other methods.
We have a professional and stable logistics, and we can deliver the package smoothly around 3 to 5 days.
Bulk Order: Shipped via sea or air, it's according to your requirement, delivery time is 7-15days after payment.
 
If you have any other questions to consult me,please not hesitate to contact me any times.
 

Details

Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips, and a feminine pattern of fat distribution in women and is important in the development and maintenance of female reproductive tissues such as the mammary glands, uterus, and vagina during puberty, adulthood, and pregnancy. It also has important effects in many other tissues including bone, fat, skin, liver, and the brain. Though estradiol levels in men are much lower compared to those in women, estradiol has important roles in men as well. Aside from humans and other mammals, estradiol is also found in most vertebrates and crustaceans, insects, fish, and other animal species.
 
Estradiol is produced especially within the follicles of the ovaries, but also in other tissues including the testicles, the adrenal glands, fat, liver, the breasts, and the brain. Estradiol is produced in the body from cholesterol through a series of reactions and intermediates.The major pathway involves the formation of androstenedione, which is then converted by aromatase into estrone and is subsequently converted into estradiol. Alternatively, androstenedione can be converted into testosterone, which can then be converted into estradiol. Upon menopause in women, production of estrogens by the ovaries stops and estradiol levels decrease to very low levels.
 
 
Estradiol
The chemical structure of estradiol.
A ball-and-stick model of estradiol.
Names
Pronunciation /??str??da?o?l/ ES-tr?-DY-ohl[1][2]
IUPAC name
(8R,9S,13S,14S,17S)-13-Methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
Other names
Oestradiol; E2; 17β-Estradiol; Estra-1,3,5(10)-triene-3,17β-diol
Properties
C18H24O2
Molar mass 272.38 g/mol
-186.6·10−6 cm3/mol
Pharmacology
G03CA03 (WHO)
License data
Oralsublingualintranasaltopical/transdermalvaginalintramuscular or subcutaneous (as an ester), subdermal implant
Pharmacokinetics:
Oral: <5%
~98%:
• Albumin: 60%
• SHBG: 38%
• Free: 2%
Liver (via hydroxylationsulfationglucuronidation)
Oral: 13–20 hours
Sublingual: 8–18 hours
Topical (gel): 36.5 hours

 

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